The involvement of cancer cells in blood leads to many types of blood cancers. The main three groups are multiple myeloma, leukemia and lymphoma. And these types are further divided into their subtypes according to their presentation. The symptoms associated with each type are usually not very different from each other and it is difficult to differentiate them only on the basis of signs and symptoms. Symptoms range from mild allergy to severe complications according to the stage of disease. Staging the disease is based on several different factors like total blood count, healthy normal cells count, bone damage and organ involvement. The cancer cells formed in the bone do not behave like normal and hence produce negative effects on the body. India is the third largest country in which blood cancers are reported. Estimated 70,000 men and women are suffering from the blood cancer with the highest rate in lymphomas. And approximately 1,00,000 cases are reported every year. Poor hygienic conditions in low-income countries and use of excessive chemical substances as in cigarette smoking are the very major risk factors. 60-90% of patients suffering from blood cancer survive in India but it is according to the stage of cancer.
The following are the blood cancer treatments that are used in clinical settings:
Chemotherapy
Immunotherapy
Radiation therapy
Bone marrow transplantation
Blood transfusion
Targeted drug therapy
These strong medicines may be given to kill blood cancer cells. Chemotherapy is used to treat cancer and may slow its spread. However, it also affects healthy cells, which may have adverse effects.
For the treatment of blood cancer, the drugs attack the environment of the cancer, it strengthens your immune system. Immunotherapy techniques include:
monoclonal antibodies
T-cell therapy.
High doses of x-rays or proton therapy will be targeted from the outside to the area of your body where the tumor is present. It eliminates blood cancer cells and reduces pain caused by cancer.
it is the use of stem cells to replace damaged blood-forming stem cells. All different types of blood cells, including platelets, white blood cells, and red blood cells, develop from these stem cells. This may be used for blood cancers that grow at a very slow rate.
Red blood cells and platelets can be replaced through blood transfusion using healthy cells from another person. For a number of reasons, certain persons with blood conditions including myeloma and lymphoma require regular transfusions of their blood.
This is a cancer treatment where certain drugs are used to destroy genetic abnormalities that cause healthy cells to become abnormal cells.
Nausea
Weakness
Paleness
Loss of appetite
Low energy to do work/ easily get tired
Fever
Flu/cold
Sweating especially during night
Loss of weight
Bone pain
Breathlessness
Headache
Abdominal pain
Infections
Skin rashes
Lymph nodes swelling
Chest pain
Coughing
Prolonged bleeding
There are certain genetic diseases which can double the risk of developing blood cancer. Some of those genetic disorders are:
Fanconi anemia
Down syndrome
Ataxia-telangiectasia
Some of the infections increase the chance of blood cancers by lowering the immunity in a person. Some viral infections are:
Epstein-Barr virus
Human immunodeficiency virus
Human T-lymphotropic virus
There is a strong association between a positive family history and developing blood cancer. It is said that your child’s siblings are more prone to this than a child.
Smoking can increase your risk of blood cancer. There are almost 7,000 compounds in cigarette smoke and many of them are causing cancers.
Radiation
The chance of developing blood cancer can increase when exposed to high radiation levels. according to a study. rates were higher in individuals who were exposed to radiation by any means.
Chemicals:
Chemicals like benzene that are used in the making of plastics, rubber, dyes, detergents, pharmaceutical companies, and insecticides, can increase the risk of cancer.
Complete blood count (CBC):
This examination counts and measures your blood cells. If there is a threat that you have blood cancer, they'll check your white blood cell counts, red blood cell counts, and platelet counts.
Computed tomography (CT) scan:
This test makes three-dimensional images of your bones and soft tissues using X-rays and a computer. A CT scan may be used to check for bone damage.
MRI:
An MRI scan may be used to check for any signs that cancer have affected your bone.
PET scan:
This examination gives pictures of your organs and tissues during movement. A PET scan may be used to check for cancer symptoms.
Biopsy:
Biopsy of your bone marrow may be performed to determine the number of normal and abnormal blood cells. They may also check a sample of your bone marrow for changes in DNA that may increase the growth of cancer.
Examining blood cells:
Clinicians may take blood samples in order to study them under a microscope and look for changes in blood cell structure.
In India, the cost of blood cancer treatment starts from one lakh, but the range is typically between four and six lakhs. But it may vary according to hospitals, medications, and treatment methods. It costs more than other diseases because it is a lengthy process. An average of eleven lakhs is required for the whole process. In India, the highest cost is about 26593 USD.
Cost of different procedure for blood cancer treatment in India:
Chemotherapy: In India, chemotherapy sessions usually cost 2175.8-543.95 USD for each treatment session.
Radiation therapy: In India radiation therapy ranges from 13296.67-2441.69 USD.
Bone marrow transplant: Depending on the complication of the procedure, the cost of a bone marrow transplant in India might range from 12087.88 to Rs 18131.82 USD.
Others: other procedures may have the cost range of a very rough estimate that is 1208- 14505 USD.
Dr. Meera Luthra
Dr. (Brig.) Anil Khetarpa
Dr. Biswajyoti Hazarik
Dr. Amrit Kaur Kaler
Dr. Amit Raodeo
Medanta Hospital
Artemis Hospital
Fortis Memorial Hospital
Max Saket Hospital
kokilaben Dhirubhai Ambani Hospital.
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