Overview of Bone Marrow Transplant Treatment in India

When a soft material inside the bone, which is known as bone marrow, becomes damaged due to any cause, it is replaced with healthy bone marrow as a treatment.  It is also known as a stem cell transplant. The bone marrow helps by producing blood cells and performing various functions. So if it becomes damaged. It can cause tremendous effects on the human body. The diseased bone marrow produces only a few blood cells and it lowers the body’s natural defense mechanism, which in turn increases the chances for many other diseases like AIDS, cancer, etc.

The Cost of Bone Marrow Transplant in India ranges from ₹ 11,20,000 to ₹ 13,70,000. The cost can vary according to the type of transplant, the experience of a surgeon, and the facilities provided by the hospitals. The management of side effects of this treatment can also affect the cost.

Types of Bone Marrow Transplant Treatment in India

Some of the important bone marrow transplant procedures are:

  • Autologous transplant
  • Allogeneic transplant
  • Umbilical cord blood transplant
  • Haplotype mismatched transplant

Autologous Transplant

In this type of transplant, doctors remove the patient’s bone marrow and save the stem cells to use it later. This usually happens when a person needs to go under chemotherapy treatment, which destroys the stem cells and reduces the immunity. After the chemotherapy, the bone marrow transplant to the patient to form a new healthy stem cell and restore function.

Allogeneic Transplant

In this type of transplant, the bone marrow cells are removed from the other person who will be the donor and whose blood antigens match the patient. The stem cells from donors given to the patient after chemotherapy or radiation therapy to restore the normal bone marrow’s function. The matching donor can be any first degree relative with the same human leukocyte antigen (HLA).

Umbilical Cord Blood Transplant

Umbilical cord is present in pregnant mothers which connects them with their baby in the uterine life. After delivery the umbilical cord was removed as there is no need for that anymore. The use of that umbilical cord blood to transplant the stem cells is the new advanced procedure to restore function of the bone marrow in diseased persons.

Haplotype Mismatched Transplant

The stem cells from the parents and siblings are sometimes only given a match of fifty percent. The use of these unmatched stem cells is now being used clinically to cure the diseased bone marrow. This can cause some complications but the procedure is selected only after weighing the pros and cons. To use this treatment, the benefits should be more than the side effects after receiving the treatment.

Procedures of the Bone Marrow Transplant

Autologous Transplant Procedure

This procedure collects the stem cells before the chemotherapy treatment. Then it is stored for a duration of chemotherapy treatment. Then after the chemotherapy ends, doctors infuse the stem cells which were previously stored. Then the proper screening will be required to check the recovery of the healthy stem cell growth.

Allogeneic Transplant Procedure

The first step is the identification of a donor which matches the receiver. After that stem cells collect from the donor either from the blood of the donor or the bone marrow and store for the duration of chemotherapy treatment. After the chemotherapy sessions end, the stem cells from the donor are injected to the patient. In the recovery phase, antibiotics are also required to decrease the chances of infections.

Cost of Bone Marrow Transplant in India

In India, the Cost of a Bone Marrow Transplant starts from ₹ 11,20,000 to ₹ 13,70,000. However, bone marrow transplant prices in India may vary according to the type of facility, patient condition, and general health.

Cost of Bone Marrow Transplant Treatment in India

Bone Marrow Transplant Treatment Cost in India Min in INR Max in INR
Bone Marrow Transplant Treatment ₹ 11,20,000 ₹ 13,70,000
Pediatric Bone Marrow Transplant ₹ 5,29,800 ₹ 11,08,000
Bone Marrow Cancer ₹ 7,50,000 ₹ 10,50,000
Haplogenic Bone Marrow Transplant ₹ 12,50,000 ₹ 15,00,000
Autologous Bone Marrow Transplant ₹ 5,28,000 ₹ 10,00,000
Allogenic Bone Marrow Transplant ₹ 9,80,000 ₹ 11,50,000

 

Cost of Bone Marrow Transplant Treatment in Different Cities of India

Bone Marrow Transplant Treatment Costs in Different Cities of India Min in INR Max in INR
New Delhi ₹ 5,00,626 ₹ 11,05,774
Gudgaon ₹ 5,72,360 ₹ 12,95,040
Noida ₹ 5,63,525 ₹ 11,55,875
Chennai ₹ 5,72,360 ₹ 11,73,205
Mumbai ₹ 5,80,094 ₹ 13,55,774
Banglore ₹ 5,68,626 ₹ 9,95,306

The little amount may vary according to the doctors’ experience and facilities provided by the hospitals.

Symptoms & Risk Factors of Bone Marrow Transplant Treatment in India

There are some of the diseases that may require bone marrow transplant for the treatment. Some of the diseases are:

  • Aplastic anemia
  • Immune deficiency virus
  • Multiple myeloma
  • Blood cancers
  • Lymphomas
  • AIDS (acquired immunodeficiency syndrome).
  • Thalassemia
  • Thrombocytosis
  • Polycythemia Vera
  • Myelodysplastic syndrome
  • Solid tumors
  • Hodgkin and non-Hodgkin lymphomas

Side Effects of AUTO Transplant

  • Nausea
  • Diarrhea 
  • Mouth blisters
  • Decreased appetite
  • Fatigue
  • Hair fall
  • Change in tastes 
  • Low platelet counts
  • Increased bleeding time
  • Anemia
  • Loss of weight
  • Infertility
  • Blurred vision
  • Sexually-transmitted diseases
  • Premature menopause
  • Thyroid diseases
  • Major organ damage like brain and lung.
  • Increased chances for cancer development.

Side Effects of ALLO Transplant

Graft versus Host disease ( the donors’ stem cells begin to destroy the healthy cells in the body).

  • Infections
  • Dry eyes
  • Dry mouth
  • Liver damage
  • Dryness of skin
  • Decrease flexibility of skin
  • Joint pain
  • Loss of weight
  • Infections
  • Breathing problems
  • Muscle pain

Some of the side effects are present in both of these treatment procedures and may not be present in all the patients. So it may vary from individual to individual.
 

Top Hospitals for Bone Marrow Transplant Treatment in India

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Fortis Malar Hospital Chennai,India

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Fortis Hospital Rajajinagar Bengaluru,India

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Fortis Hospital Shalimar Bagh New Delhi,India

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Max Super Speciality Hospital, Bathinda Bathinda,India

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Manipal Hospital, Pune Pune,India

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Top Doctors for Bone Marrow Transplant Treatment in India

Empower your Health with the Expertise of Leading Medical Professionals.

Dr. Suresh H Advani

Department of Medical Oncology

Sr Consultant

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Dr. Pravas Chandra Mishra

Department of Oncology

Director

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Dr. Sameer A. Tulpule

Department of Bone Marrow Transplant, Medical Oncology & Hematology

Consultant

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Dr. Santanu Sen

Department of Transplant

Consultant

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Dr Suhail Qureshi

Department of Bone Marrow Transplant & Medical Oncology

Consultant Medical Oncology

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Treatment Costs for Bone Marrow Transplant Treatment in India

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Steps for Bone Marrow Transplant Treatment in India

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FAQ's of Bone Marrow Transplant Treatment

Some of the commonly observed signs and symptoms are: Joint pain, Muscle pain, Breathlessness, Cough, Dry eyes, Scarring on the skin, Rashes, Yellow tint in sclera of the eye, Dry mouth and Sores in the mouth

The survival rates after a bone marrow transplant can vary considerably from case to case. For example, Survival rates for a person with non-malignant condition are 70-90% if he gets donor cells from a related sibling and 36-65% if the donor cells are taken from an unrelated donor.

It may be 3-4 weeks according to the procedure performed on the patient.

It may be 3-4 weeks according to the procedure performed on the patient.