Bone Marrow Transplant Treatment in India

Types of Bone Marrow Transplant Treatment in India

Some of the important bone marrow transplant procedures are:

• Autologous transplant
• Allogeneic transplant
• Umbilical cord blood transplant
• Haplotype mismatched transplant

Autologous Transplant

In this type of transplant, doctors remove the patient’s bone marrow and save the stem cells to use it later. This usually happens when a person needs to go under chemotherapy treatment, which destroys the stem cells and reduces the immunity. After the chemotherapy, the bone marrow transplant to the patient to form a new healthy stem cell and restore function.

Allogeneic Transplant

In this type of transplant, the bone marrow cells are removed from the other person who will be the donor and whose blood antigens match the patient. The stem cells from donors given to the patient after chemotherapy or radiation therapy to restore the normal bone marrow’s function. The matching donor can be any first degree relative with the same human leukocyte antigen (HLA).

Umbilical Cord Blood Transplant

Umbilical cord is present in pregnant mothers which connects them with their baby in the uterine life. After delivery the umbilical cord was removed as there is no need for that anymore. The use of that umbilical cord blood to transplant the stem cells is the new advanced procedure to restore function of the bone marrow in diseased persons.

Haplotype Mismatched Transplant

The stem cells from the parents and siblings are sometimes only given a match of fifty percent. The use of these unmatched stem cells is now being used clinically to cure the diseased bone marrow. This can cause some complications but the procedure is selected only after weighing the pros and cons. To use this treatment, the benefits should be more than the side effects after receiving the treatment.

Procedures of the Bone Marrow Transplant

Autologous Transplant Procedure

This procedure collects the stem cells before the chemotherapy treatment. Then it is stored for a duration of chemotherapy treatment. Then after the chemotherapy ends, doctors infuse the stem cells which were previously stored. Then the proper screening will be required to check the recovery of the healthy stem cell growth.

Allogeneic Transplant Procedure

The first step is the identification of a donor which matches the receiver. After that stem cells collect from the donor either from the blood of the donor or the bone marrow and store for the duration of chemotherapy treatment. After the chemotherapy sessions end, the stem cells from the donor are injected to the patient. In the recovery phase, antibiotics are also required to decrease the chances of infections.

Cost of Bone Marrow Transplant in India

In India, the Cost of a Bone Marrow Transplant starts from ₹ 11,20,000 to ₹ 13,70,000. However, bone marrow transplant prices in India may vary according to the type of facility, patient condition, and general health.

Cost of Bone Marrow Transplant Treatment in India

Cost of Bone Marrow Transplant Treatment in Different Cities of India

The little amount may vary according to the doctors’ experience and facilities provided by the hospitals.

Symptoms & Risk Factors of Bone Marrow Transplant Treatment in India

There are some of the diseases that may require bone marrow transplant for the treatment. Some of the diseases are:

• Aplastic anemia
• Immune deficiency virus
• Multiple myeloma
• Blood cancers
• Lymphomas
• AIDS (acquired immunodeficiency syndrome).
• Thalassemia
• Thrombocytosis
• Polycythemia Vera
• Myelodysplastic syndrome
• Solid tumors
• Hodgkin and non-Hodgkin lymphomas

Side Effects of AUTO Transplant

• Nausea
• Diarrhea 
• Mouth blisters
• Decreased appetite
• Fatigue
• Hair fall
• Change in tastes 
• Low platelet counts
• Increased bleeding time
• Anemia
• Loss of weight
• Infertility
• Blurred vision
• Sexually-transmitted diseases
• Premature menopause
• Thyroid diseases
• Major organ damage like brain and lung.
• Increased chances for cancer development.

Side Effects of ALLO Transplant

Graft versus Host disease ( the donors’ stem cells begin to destroy the healthy cells in the body).

• Infections
• Dry eyes
• Dry mouth
• Liver damage
• Dryness of skin
• Decrease flexibility of skin
• Joint pain
• Loss of weight
• Infections
• Breathing problems
• Muscle pain

Some of the side effects are present in both of these treatment procedures and may not be present in all the patients. So it may vary from individual to individual.